Random Analogies
"Barr's research involves a mutation in a region of the DNA directly before the CRH gene, called the CRH promoter. In a sense, a gene's promoter is like password protection for the gene. If the cell doesn't use the proper combination of factors to satisfy the password, the instructions in the gene cannot be accessed. Other times, a faulty promoter will allow access to the gene too often. In the current study, the mutation in the promoter for CRH causes the cell to make too much CRF. "
"Messenger RNA is like a ball of string; you need to know which areas are available for binding," says Darrin Disley, head of marketing at ExpressOn. "The current technology has you snip one base at a time, but a gene can have 10,000 bases so you have to do so many experiments. There's a very high failure rate; it's expensive and slow."
This kinda like a horse is a horse is a horse, of course.

