"Whereas competitive inhibition can be overcome by increased substrate/reactant concentration; non-competitive inhibition cannot be. Competitive inhibition is like sitting on a seat in musical chairs, so others can't sit on it. You'll have to get off eventually, so increased substrate/reactant will eventually defeat you."
"Non-competitive inhibition is like smashing that chair, so no one can sit on it, ever again."
" Competitive Inhibition: When there's another molecule that isn't a substrate, yet can bind to the active site of an enzyme. – Penicillin, for example, blocks an enzyme used by bacteria to make cell walls. – Antabuse (disulfiram) is a commercial drug that treats alcoholism by inhibiting the enzyme that breaks down alcohol, leading to severe hangover and illness within 5-10 minutes after drinking. Competitive inhibition can be overcome by increasing substrate concentration. – In other words, substrates can out- compete inhibitors. Analogy: Competitive inhibition is like someone sitting in your seat. "
METAMIA is a free database of analogy and metaphor. Anyone can contribute or search. The subject matter can be anything. Science is popular, but poetry is encouraged. The goal is to integrate our fluid muses with the stark literalism of a relational database. Metamia is like a girdle for your muses, a cognitive girdle.