point mutation
"A point mutation is like a typo in the gene that causes it to work incorrectly."
This type of mutation is not a major
change in a DNA sequence. But they usually occur at a key position within the gene. For example, a single point mutation in the protein coding region of a gene may have a deleterious effect on the creation of that protein.
The word spelling analogy may give a feel for this change. A single change in a letter in some words may change the word into something that is not recognized. For example , if "butler" is change to "butter", the meaning of that word is entirely different, even though only a single letter, l to t, has been modified.

METAMIA is a free database of analogy and metaphor. Anyone can contribute or search. The subject matter can be anything. Science is popular, but poetry is encouraged. The goal is to integrate our fluid muses with the stark literalism of a relational database. Metamia is like a girdle for your muses, a cognitive girdle.