dna polymerase

What: "You need to have a way to fix mistakes., or a proofreading capacity. Each of your cells has 46 DNA moleucles, about 6 billion bases. It only takes a few hours to copy all of this with very few errors. The DNA polymerase is like a word processor. When it sees a mistake it will back up and fix it like hitting the delete key on a computer."

Writer: Ms. Steinhardt

LCC:

Where: Reference Link Has Evaporated

Date: May 6 2013 9:45 AM

What: "DNA polymerase cannot build "random" DNA molecules through the willy-nilly polymerization of nucleotides. It can only make copies of DNA molecules that already exist. Think of it this way -DNA polymerase is like a copy machine, NOT like a type writer, and a copy machine cannot print anything unless it has a template to work with."

Writer: Not Stated

LCC:

Where:

Date: May 6 2013 9:48 AM

What: "To the contrary, the open binding site of DNA Polymerase is like an available parking spot--anything can drive in [DNA Pol with just a funnel as a binding site, with base pairing positions of template visible at bottom]. There will, however, be constraints on what nucleotides stay in the pocket" The link is a detailed discussion of DNA replication.

Writer: Not Stated

LCC:

Where:

Date: May 6 2013 9:51 AM

What: "DNA polymerase is like a vehicle that buses in the individual nucleotides. It builds the daughter strand of DNA according to the template set up by the parental strand."

Writer: Not Stated

LCC:

Where:

Date: May 6 2013 9:53 AM

What:

"If the DNA polymerase is a genetic photocopier, an RNA polymerase is like a genetic fax machine: it produces a copy of the gene for transmission from the cell's nuclear headquarters to its cytoplasmic manufacturing facility."

Fax machines aren't as common as they used to be.

Writer: Gail Dutton, Jeffrey M. Perkel

LCC:

Where:

Date: Sep 12 2014 11:30 AM