complement system
"The complement system is like a molecular alarm system and first responder, Grice explains. "It leads the counterattack against microbial insult." The system is an evolutionarily ancient branch of the immune response and a key function is marking microbial and dying host cells for elimination."
"The complement system is like a Rube Goldberg Device Similar in that it is circular, hard to know where it begins and it is extremely complicated can never understand a component of the pathway without knowing what is upstream/downstream of that specific component"
"This complement system is like a sword which is sharp at both edges. Excessive activation of the complement leads to various disease like rheumatoid arthritis, glomerulonephritis, multiple sclerosis and other inflammatory diseases."

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