allosteric inhibition


Tuning An Enzyme

a: Allosteric inhibition ~
b: latch on the handles of a pair of scissors

What: "Allosteric inhibitors work in a very different way-they bind to a totally different site, regulate the conformational preferences and/or flexibility of the entire target protein, and thereby disable the active site. Allosteric inhibition is like putting a latch on the handles of a pair of scissors in order to prevent the blades from being able to open and close and cut things."

Writer: Professor Arthur J. Olson et al.
Date: Oct 8 2014 4:42 PM

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