"The clathrin surrounds the involuting patch of membrane, which then pinches off to form the tiny vesicles. One way to envision the process is to imagine yourself in the fruit and vegetable aisle of the grocery store. Receptor-mediated endocytosis is like putting your hand inside a plastic bag, grabbing a bunch of green beans, and then turning the bag inside out around them. "

"Receptor mediated endocytosis is like pinocytosis except it is highly
specific. Animal cells use this type of endocytosis to transport specific
macromolecules from the environment."