What:

"The estrogen receptor is like a keyhole in a locked door, and estrogen is the key that opens that door and "turns on" growth-promoting effects in the cell. However, among dozens of keys, you might find some that fit into the keyhole but do not work to turn the lock and open the door."

Writer: Jeanne Wallace

LCC:

Where:

Date: Mar 23 2016 8:18 PM

What:

"The discovery comes from detailed studies of the transmembrane protein straddling the worlds inside and outside of lymphocytes and other cells of the immune system. These receptor proteins are like spokes piercing the cell membrane. Part of the receptor pokes into the cell and part extends out from the cell surface. The external "domain" receives signals from outside the cell which regulate responses inside -- ranging from increasing the cell's glucose supply to starting a new cell division cycle to generate more lymphocytes."

Writer: Not Stated

LCC:

Where:

Date: Aug 6 2017 8:12 PM

What:

"Typical nuclear receptor proteins are like sensors, registering a specific molecular event and responding accordingly, generally by altering gene expression patterns. So, Lazar asked, "What is the purpose of having a system that responds to changes in cellular heme levels?" He hypothesized that the sensor could act to regulate heme itself."

Writer: Mitchell Lazar, MD, PhD, Director of Penn’s Institute for Diabetes, Obesity, and Metabolism

LCC:

Where:

Date: Aug 6 2017 8:15 PM

What: "Let's pretend that the defective receptor is like a gate with a broken lock and the hormone is a goat. Without the gate to keep the hormone where it's supposed to be, it wanders around to neighbors' yards and eats all their grass. So certain people have "damaged lawns," all because of a faulty gate."

Writer: Ellen Kuwana

LCC:

Where:

Date: May 14 2013 2:09 PM

What: Think of a cellular receptor as a glove and its ligand as a baseball. They are made for each other. One captures the other. Now think about a baseball glove with a large softball in it. The glove can no longer effectively capture the baseball because there is another ball blocking the pocket. It much more complicated than this, but the essence is something is blocking something else.

Writer: Lucrezia

LCC:

Where: Reference Link Has Evaporated

Date: Jan 22 2015 9:53 AM

What:

"The retina is the layer of photoreceptor cells that make up the very back of the eye. In many ways, the retina works like a digital camera*. The photoreceptor cells are like individual pixels, and the brain puts all these pixels together to make a single image."

Writer: Not Stated

LCC:

Where:

Date: Mar 11 2015 10:54 AM

What:

"How a retinal prosthesis works. Photoreceptor cells are like tiny cameras in the retina that convert light to electrical signals and send them to the brain. These cells are killed by diseases like macular degeneration and retinitis pigmentosa, causing loss of vision."

Writer: Peyman Pakzaban,

LCC:

Where:

Date: Mar 11 2015 10:56 AM

What:

"Cancer cells have a high requirement for folic acid as it is necessary for their metabolism, so the cells have 500 times more folate receptors compared with a healthy cell, explains Castillo-León. The receptors are like antennas on the surface of the cell membrane that seek out folic acid. The cancer cells interact with the electrochemical platform, resulting in a decrease in the current being measured. The sensor allows the detection of cancer cells at a concentration as low as 250 cells per millilitre."

Writer: Castillo-León

LCC:

Where:

Date: Sep 1 2014 2:25 PM

What:

"Cell-surface receptors are like traffic cops. . . . Without the appropriate signals entering and exiting the stem cell, it does not know whether to selfrenew..."

The rest is in the link....

Writer: Joseph A. Amato

LCC:

Where:

Date: Feb 12 2015 1:20 PM

What:

"Cell-surface receptors are like radiowave antennae: They pick up signals to send them forward to the appropriate cellular equipment that process the information in the signals. But how do cells know where to best position receptors to cleanly and efficiently pick up the numerous signals coming at them? "

A paper on how cells organize the receptors on their outer surfaces...

Writer: Rajendrani Mukhopadhyay

LCC:

Where:

Date: Feb 12 2015 1:24 PM