a: Topoisomerase ~
b: several enzymes in one
What:
"Because drugs act on specific enzyme conformations, knowledge of these conformations has significant implications in drug design. "Topoisomerase is like several enzymes in one because its various conformations are so different," Dr. Wang said. "Each one is a potential drug target." Many anticancer drugs, initially recognized for their ability to kill cells, have turned out to target topoisomerases, Dr. Wang said. Among these are doxorubicin (Adriamycin), etoposide, and mitoxantrone."
Useful?
Writer: Dr. James C. Wang
LCC:
Where:
Date: Jan 31 2015 8:23 PM
# 7193 Critique Analogy