a: missing stop codon ~
b: stuck assembly line

What:

"When mRNA is accidentally missing a stop codon, however, the ribosome is like an auto manufacturing plant that can't get a car off the end of the line-the line stalls and production stops. "In addition, these defective mRNA are problematic because they are translated into aberrant proteins"


Useful?
Writer: Claudio Joazeiro
LCC:
Where:
Date: Oct 8 2014 4:25 PM


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