Linker Histone As Archivist

a: Cell nucleus ~
b: an overcrowded archives

What: "The cell nucleus is like an overcrowded archives, with DNA and proteins wound and twisted into dense packages, called chromatin. Now a series of experimental results, including one reported in this issue (p. 614), is sketching a new picture of this archive and how a protein called the linker histone helps to manage it, by either granting or denying the cell's gene-regulating proteins access to particular sequences."

Writer: Elizabeth Pennisi
Date: Feb 12 2014 1:03 PM

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