What: "Sodium is like the thermostat of a cell," Dr. Fehlings said. "When the cell is injured, sodium enters. That's why tissues swell. The cell tries to pump it out, which makes it worse, because calcium then goes into the cell. It results in what biologists call a positive feedback loop. So the rationale at looking at sodium channel blockers is clear." A major multi-center, randomized, controlled trial is expected to begin in early 2013.

Writer: Michael Fehlings, MD

LCC:

Where: Reference Link Has Evaporated

Date: Nov 13 2012 6:26 PM