"ELI5: Glitter = HIV, Vacuum = treatment. Coins on floor = good cells

You have to vacuum your room and have to pick up EVERY glitter particle. Here's the catch, the glitter can replicate if you do not remove every single particle. While you are vacuuming (taking antiviral therapy), you have to make sure not to suck up the coins on the floor (uninfected cells). You can see quickly that it is very hard to "100% vacuum" your room"