"But central to the function of the system is the amplifier, and HER2 is like the amplifier of the stereo system. Whatever media is being played on whichever kind of player, it's all being amplified by HER2.
And so that would explain the pathology of HER2 in breast cancer, as well, because when HER2 gene is amplified, there is too much of the amplifier. And it's like, you know, turning the volume all the way up on the record player. And when that happens in breast cancer, it drives the cells to proliferate like crazy, which is what accounts for the poor prognosis in breast cancer. "