Tuning An Enzyme
a: Allosteric inhibition ~
b: latch on the handles of a pair of scissors
What: "Allosteric inhibitors work in a very different way-they bind to a totally different site, regulate the conformational preferences and/or flexibility of the entire target protein, and thereby disable the active site. Allosteric inhibition is like putting a latch on the handles of a pair of scissors in order to prevent the blades from being able to open and close and cut things."
Useful?
Writer: Professor Arthur J. Olson et al.
LCC:
Where:
Date: Oct 8 2014 4:42 PM
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